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  Contact : 085-0290011

De Boelelaan 1065, 1082 SB Amsterdam (Netherlands)

Prof. Dr. Ioannis G. Pallikaris

Refractiechirurgie, cornea-, staar-, Intra-oculaire lens-en keratoconusspecialist

Afspraak

Prof. Dr. Ioannis Pallikaris

Medisch directeur

Prof. Dr. Ioannis Pallikaris heeft de afgelopen 40 jaar baanbrekende methoden en technieken ontwikkelt binnen de oogheelkunde. Hierdoor is hij inmiddels wereldberoemd, staan er 20 patenten op zijn naam en heeft hij 15 internationale awards ontvangen.

Als uitvinder van ooglaserbehandelingen, wordt hij ook wel de “vader van LASIK” genoemd. De eerste methode van ooglaseren. Een lange periode was hij rector van Girit Universiteit (Kreta-Griekenland) en is daar momenteel nog erevoorzitter.

Om chirurgen vanuit de hele wereld trainingen te geven en aan kennis over te dragen heeft hij al meer dan 200 lezingen op Universiteiten en medische congressen gegeven. Ook heeft hij voor dezelfde doelen het “Vardinoyannion Oog Instituut opgericht”. Pallikaris is voorzitter van de European Society of Cataract & Refractive Surgeons (ESCRS) en in 2014 benoemd tot de groep van ‘100 meest invloedrijke oogartsen’ ter wereld.

Nog steeds is Prof. Dr. Ioannis Pallikaris actief binnen de oogheelkunde op het gebied van R&D, onderwijs en supervisie. Samen met een team ingenieurs en fysici werkt hij meerdere dagen per maand aan de verdere ontwikkeling en innovatie in de medische technologie. En als medisch director van Worldeye is zijn invloed en kennis nog dagelijks voor vele patiënten bereikbaar.

  • Aristotle University of Thessaloniki, Greece in 1972
  • PhD thesis at the University of Zurich, Switzerland in1981.
  • The University of Munich (Institute of Physiological Optic, 1978)
  • The University of Vienna (Ultrasound in Ophthalmology, 1979)
  • University of Zurich (Department of microvascular surgery, 1980)
  • The Hippocration Hospital of Thessaloniki, Greece (1981-1986)
  • Director of the Ophthalmology Clinic Hospital of Chania, Greece (1986-1988)
  • Associate Professor of Ophthalmology at the School of Medicine, University of Crete in 1988
  • Professor of Ophthalmology at the University of Crete since 1996.
  • director of the Vardinoyannion Eye Institute of Crete (VEIC, 1989)
  • Institute of Vision and Optics (IVO, 2005), chairman of the Department of Ophthalmology at the University of Crete,
  • the director of the Eye Clinic of the University Hospital of Heraklion, Greece (1996-2004)
  • The rector of the University of Crete from 2004 to 2011
  • The president of the European Society of Cataract and Refractive Surgeons (ESCRS – 2006-2008)
  • The ESRCS as an elected Board member (2011)
  • An elected member of Academica Ophthalmologica Internationalis (2010).
  • 80 International Conferences from 1998-2003.
  • 215 presentations in International Conferences.
  • 153 presentations in Greek Conferences.
  • Coordinator of the “Aegean Cornea” and “Aegean Retina” Conferences on a biannual basis in collaboration with the Harvard Medical School, and of the “Summer School in Visual Optics” on a yearly basis.
  • 1 “Charles D. Kelman Innovator’s Award” (American Society of Cataract & Refractive Surgeons) ASCRS 2003
    2 “Barraquer Award” (International Society of Refractive Surgeons) ISRS 1997
    3 The “Casebeer Award” (International Society of Refractive Surgeons) ISRS 2002
    4 “Albrecht-von-Graefe-Vorlesung” Award for the Innovator’s DOC 2003
    5 KMSG-Barraquer Award (American Academy of Ophthalmolgy) AAO 1999
    6 Award as pioneer in Refractive Surgery SUMMIT Tech. 1998
    7 Achievement Award (American Academy of Ophthalmolgy) AAO 2000
    8 President of the European Society of Cataract and Refractive Surgeons ESCRS 2006 – 2008
    9 Member of the Board of Directors ISRS 2001
    10 Vice President of the “Excimer Laser European Ophthalmologic Society” ELEOS 1991/95
    11 Member of the “Glory” Certification Committee ISRS 1999
    12 Chairman of the International Training Center Sub-Committee (ISRS) ISRS 1999
    13 Honorary member of the International Microsurgery Society
    14 President of ERELAS (European Refractive Laser Study) ERELAS 1995
    15 Chairman of the International Investigator’s T-PRK Study Group 1994
    16 President of the National Research Committee for Biotechnology in Greece ESET 2006-7
    17 Binkhorst Medal ESCRS 2009
    18 Academia Ophthalmologica Internationalis AOI 2010
    19 Elected Board memberof the European Society of Cataract and Refractive Surgeons ESCRS 2011
    20 Barraquer Award ‘Video Refractive Italy’ 2011
    21 Charamis medal SOE 2013
    22 Hospital LASIK & SMILE-Pallikaris Ioannis India 2015
    23 member of The Ophthalmologist’s 2016 Power List – at number 18 2016
    24 THE THIRD BIONIC EYE SURGERY –PATIENT SERKAN ÇEÇEN Istanbul 2016
  • Editor of 3 books about ophthalmology
  • Pallikaris IG. “Physiologischer Optic”, 1980.
  • Pallikaris IG, Siganos DS. LASIK. Slack Inc. Therofare NJ, USA, 1998
  • Agarwal, Pallikaris IG, Knorz MC. Refractive Surgery. Jaypee Bros. Inc. 1999
  • Principles and applications of retinal ray tracing (Tracey) aberrometry. Molebny VV, Pallikaris IG, Molebny SV, Ginis HS
  • GD Kymionis, CS Siganos, IG Pallikaris : Innovative techniques in ophthalmology
  • Chapters in foreign scientific books
  • Pallikaris IG, Siganos DS. Lasik Complications management in Talamo JH., Kruger RR. The Εxcimer Μanual. Little Brown and Company. Boston, New York, Toronto, London, 1997: 227-243.
  • Pallikaris IG, Siganos DS. Refractive Surgery in Greece and the Mediterranean Area. In Elander R, Rich LF, Robin JB Eds. Principles and Practice of Refractive Surgery. W.B. Saunders Co., Philadelphia PA, USA. 1997: 599-610.
  • Siganos DS., Pallikaris IG. Clear Lensectomy and Intraocular Lens Implantation in High Hyperopia. In Long D, Ed. Cornea and Refractive Surgery. Kugler Publications. The Hague, Netherlands. 1998: 257-266
  • Pallikaris IG, Siganos DS. A New Optical Effect of Arcuate Keratotomy Treatment of Small or Decentered Excimer Laser Ablation Zones. In Lomg D, Ed. Cornea and Refractive Surgery. Kugler Publications. The Hague, Netherlands. 1998: 275-282.
  • Pallikaris IG, Siganos DS. Alk and lasik Study. In Casebeer JC, Ruiz L, Slade S, Eds. Lamellar Refractive Surgery. SLACK Inc. Thorofare NJ, USA. ISBN 1-55642-286-5 384 pp, 1998.
  • Siganos DS, Pallikaris IG. Preoperative Evaluation. Chapter 11, in Pallikaris IG, Siganos DS Eds. LASIK. SLACK Inc. Thorofare NJ, USA. 1998: 123-128.
  • Siganos DS, Pallikaris IG. Papadaki TG. The procedure. Chapter 12, in Pallikaris IG, Siganos DS Eds. LASIK. SLACK Inc. Thorofare NJ, USA. 1998: 129-136.
  • Siganos DS, Pallikaris IG. Postoperative management. Chapter 13, in Pallikaris IG, Siganos DS Eds. LASIK. SLACK Inc. Thorofare NJ, USA. 1998: 137-140.
  • Siganos DS, Pallikaris IG, Papadaki TG, Katsanevaki VI, Evangelatou K. Results of LASIK for the Treatment of Myopia at 1 year from the University of Crete and the Vardinoyannion Eye Institute of Crete. Chapter 23 (insert), in Pallikaris IG, Siganos DS Eds. LASIK. SLACK Inc. Thorofare NJ, USA. 1998: 253-254.
  • Pallikaris IG, Siganos DS., Katsanevaki VI., Complications and their Management. Chapter 24. (insert The PALM technique Photo-Ablated), in Pallikaris IG, Siganos DS Eds. LASIK. SLACK Inc. Thorofare NJ, USA. 1998: 277.
  • Pallikaris IG, Siganos DS. A New Optical Effect of Arcuate Keratotomy. Chapter 26. In Pallikaris IG, Siganos DS Eds. LASIK. SLACK Inc. Thorofare NJ, USA. 1998: 297-302.
  • Pallikaris IG, Kapoulas PV, Siganos DS. An Alternative topography in LASIK. Chapter 31. In Pallikaris IG, Siganos DS Eds. LASIK. SLACK Inc. Thorofare NJ, USA. 1998: 359-362.
  • Pallikaris IG, Siganos DS, Papadaki TG. The Procedure. Chapter 17. In Machat JJ, Slade SG, Probst LE, Eds. The Art of LASIK (2nd Edition). SLACK Inc. Thorofare NJ, USA. 1998: 201-206.
  • Pallikaris IG, Siganos DS, Katsanevaki VI. LASIK Complications and their Management. Chapter 31. In Machat JJ, Slade SG, Probst LE, Eds. The Art of LASIK (2nd Edition). SLACK Inc. Thorofare NJ, USA. 1998: 359-369.
  • Pallikaris IG, Papadaki TG, Siganos DS, Lawless M, Doane JF, Buratto L, Probst LE, Woolfson J. Case complications. Chapter 42. In Machat JJ, Slade SG, Probst LE, Eds. The Art of LASIK (2nd Edition). SLACK Inc. Thorofare NJ, USA. 1998: 481-507.
  • Pallikaris IG, Papadaki TG. From Keratomileusis-in-situ to LASIK. The Evaluation of Lamellar Corneal Procedures. Chapter 20. S. Agarwal, Pallikaris IG, Knorz MC. Refractive Surgery. Jaypee Bros. Inc. 1999
  • V. Molebny, I. G. Pallikaris, S. I. Panagopoulou, J. Brandau, J. S. Wakil. Tracey Retinal Ray Tracing Technology Ingoing Adjustable Refractometry. In: Customized Corneal Ablation: the Quest for SuperVision, S. M. MacRae, R. R. Krueger, R. A. Applegate, Eds., SLACK Inc., Thorofare, NJ, USA, 2000.
  • Phakic refractive lens (PRL) for treating high myopia. M Κalyvianaki, GD Kymionis, IG Pallikaris. Step by step. Lenticular refractive surgey. A Garg, JL Alio, D Dementiev, AA Marinho Jaypee Brothers, New Delhi, pp:153-165
  • LASIK outcomes IG Pallikaris, GD Kymionis The Cornea, C.S. Foster, DT Azar, CH Dohlman Smolin and Tauft, Lippcott-Williams, 2004, pp 1217-1229
  • Phakic Intraocular Lenses for the treatment of high myopia M Kalyvianaki, GD Kymionis, IG Pallikaris Chapter 16, Ophthalmology Research: Visual Prosthetics and Ophthalmic Devices: New Hope in Sight J Tombran-Tink, CJ Barnstable and J F Rizzo III
  • Mastering the techniques of corneal refractive surgery GD Kymionis, CS Siganos, IG Pallikaris A Garg, IG Pallikaris, JE Hoyos, R Pinelli, Jaypee Brothers, Medical Publishers Ltd, New Delhi, India, 2006, pp:287-291
  • Phakic Refractive Lens (PRL™) for treating high myopia M. Kalyvianaki, G. Kymionis, I. Pallikaris Mastering the techniques of lens based refractive surgery A Garg, J Alio, Dementiev, A Marinho Jaypee Brothers, Medical Publishers Ltd, New Delhi, India, 2005, pp: 102-107
  • Intacs GD Kymionis, CS Siganos, IG Pallikaris Step by step. Corneal refractive surgery A Garg, IG Pallikaris, D. Dementiev, R Pinelli, Jaypee Brothers, Medical Publishers Ltd, New Delhi, India, 2006, pp:173-183
  • Marking the cornea and creation of corneal flap P Titze, A Khoury, G Kymionis, G Kounis, I Aslanides, I Pallikaris LASIK surgery: step by step RB Vajpayee, N Sharma, SA Melki, L Sullivan Jaypee Brothers, Medical Publishers Ltd, New Delhi, India, 2003, pp: 68-75
  • Laser ablation and flap repositioning A Khoury, P Titze, G Kymionis, S. Plainis, I Aslanides, I Pallikaris LASIK surgery: step by step RB Vajpayee, N Sharma, SA Melki, L Sullivan Jaypee Brothers, Medical Publishers Ltd, New Delhi, India, 2003, pp: 75-82
  • The PALM technique for the treatment of Irregular Astigmatism. Pallikaris IG, Katsanevaki VJ, Ginis HS. In: Treatment of irregular astigmatism. Alio H et al.
  • Epi-LASIK: A new refractive Technique. Histological Evaluation and Human Study. Pallikaris IG, Naoumidi II, Kalyvianaki MI, Ginis HS. In Wavefront and emerging technologies. Pp 181-187 2003 Kugler Publishing.
  • A Garg, IH Fine, IG Pallikaris, DF Chang, H Tsuneoka, JJ Bovet Jaypee Brothers, Medical Publishers Ltd, New Delhi, India, 2006, pp:133-137
  • Kymionis GD, Aslanides IM, Panagopoulou, SI, Plainis S, Astyrakakis N, Pallikaris IG (2004). Topographically Supported Customized Ablation (TOSCA) for the management of decentered Laser in situ Keratomileusis (LASIK). American Journal of Ophthalmology, 137(5): 806-11.
  • Katsanevaki V, Panagopoulou SS, Plainis S, Ginis, HS and Pallikaris IG (2004). Accommodation dynamics and its implication on customised corrections. Chapter 13 in Wavefront customised visual correction: The Quest for Super Vision II, edited by Krueger RR, Applegate RA and MacRae SM, SLACK incorporated, pp 115-120.
  • Panagopoulou S, Plainis S, MacRae SM, and Pallikaris IG (2004). Implications of pupils size and accommodation dynamics on customised wavefront-guided refractive surgery. Chapter 14 in Wavefront customised visual correction: The Quest for Super Vision II, edited by Krueger RR, Applegate RA and MacRae SM, SLACK incorporated, pp 121-126. Plainis S, Panagopoulou S, Katsanevaki V, Ginis HG and Pallikaris IG (2003). Dynamics of the accommodation system: implications on customised laser ablations. Chapter 20 In Wavefront analysis, aberrometers and corneal topography, Edited by Boyd B and Agarwal A, Highlights in Ophthalmology, pp 323-330.
  • Khoury A, Titzé P, Kymionis GD, Plainis S, Aslanides IM and Pallikaris IG (2003). Laser ablation and flap repositioning. In Step by step LASIK surgery, edited by Vajapyee RB, Sharma N, Melki SA and Sullivan, L. Jaypee Brothers, New Delhi.
  1. Device for measuring aberration refraction of the eye

Molebny, Vasyl V., Pallikaris, Ioannis, Chyzh, Igor, Sokurenko, Vyacheslav, Naoumidis, Leonidas, Wakil, Youssef, Tracey Technologies, L.L.C.

An instrument for measuring aberration refraction of an eye is provided, having: a lens system defining an instrument optical axis and an alignment device for aligning the visual axis of the eye with the instrument optical axis. A light source ( 1 )…

  1. Method And Device For Determining Refractive Components And Visual Function of the Eye For Vision Correction

WAKIL, Youssef, S., MOLEBNY, Vasyl, PALLIKARIS, Ioannis, G., MOLEBNY, Sergiy, PADRICK, Tom, TRACEY TECHNOLOGIES, LLC

A method and an instrument is provided for measuring aberration refraction of an eye with a first device for measuring the total aberration refraction of the eye and a second device for measuring the aberration refraction of the cornea of the…

  1. Device and method for the increase of ocular elasticity and prevention of macular degeneration

Pallikaris, Ioannis, Tsllibaris, Miltiadis K., Kounis, George A., Kymionis, George D., Harilaos, Ginis S.

A compressible implant for the increase of ocular elasticity and the prevention of macular degeneration is provided. This implantable intraocular device, which can be used for the prevention of ocular degeneration and especially of the macular…

  1. Device for separating the epithelium layer from the surface of the cornea of an eye

Pallikaris, Ioannis, Ginis, Harilaos S., FOS Holding S.A.

An automated mechanical device separates the epithelial layer of a cornea from the cornea. The device includes a separator such as a plate, wire or dull blade. The device can preserve a separated epithelial layer as a disk without rupturing the disk…

  1. Device for the shaping of a substance on the surface of a cornea

Pallikaris, Ioannis, Ginis, Harilaos

A device for helping to correct imperfections of a cornea includes a molding lens. The molding lens includes an external surface having a concave shape to correspond to the desired shape of the cornea. Heating and cooling elements are located with the…

  1. Photoablatable lenticular modulator

Pallikaris, Ioannis G.

Photoablatable modulator for use in Laser ablation processes on the cornea consisting of a mixture of collagen and vegetable gelatins which is formed in situ on the corneal surface to be treated. A small quantity of a solution at a temperature higher…

  1. Method and device for synchronous mapping of the total refraction non-homogeneity of the eye and its refractive components

Molebny, Vasyl V., Pallikaris, Ioannis, Wakil, Youssef, Molebny, Sergiy, Tracey Technologies, LLC

An instrument for measuring aberration refraction of an eye is provided, having: a lens system defining an instrument optical axis and an alignment device for aligning the visual axis of the eye with the instrument optical axis. A light source…

  1. Measuring Refractive Characteristics of Human Eyes

WAKIL, Youssef, PALLIKARIS, Ioannis, MOLEBNY, Vasyl, TRACEY TECHNOLOGIES, LLC

An apparatus and method for measuring refractive characteristics of human eyes with an objective refraction measuring device for measuring refraction in at least one eye, the objective refraction measuring system (10) having a proximal end and a…

  1. DEVICE FOR SEPARATING THE EPITHELIUM LAYER FROM THE SURFACE OF THE CORNEA OF AN EYE

PALLIKARIS, Ioannis, GINIS, Harilaos, FOS HOLDING S.A.

A device is disclosed for separating the epithelial layer of a cornea from the eye. The device includes a separator having an edge to remove the epithelial layer as the separator moves across the eye. The edge includes a thickness thicker than the…

  1. DETERMINING CLINICAL REFRACTION OF EYE

WAKIL, Youssef, MOLEBNY, Vasyl, MOLEBNY, Sergiy, PALLIKARIS, Ioannis, TRACEY TECHNOLOGIES, LLC

A method of measuring eye refraction to achieve desired quality according to a selected vision characteristics comprising the steps of selecting a characteristic of vision to correlate to the desired quality of vision from a group of vision…

  1. METHOD AND DEVICE FOR SYNCHRONOUS MAPPING

MOLEBNY, Vasyl, PALLIKARIS, Ioannis, WAKIL, Youssef, MOLEBNY, Sergiy, TRACEY TECHNOLOGIES, LLC

An instrument is provided for synchronously measuring refraction errors of the optical system of an eye and its refractive components, having: a lens system defining an instrument optical axis and an alignment device for aligning the visual axis of…

  1. DEVICE FOR THE SHAPING OF A SUBSTANCE ON THE SURFACE OF A CORNEA

GINIS, Harilaos, PALLIKARIS, Ioannis

A device for helping to correct imperfections of a cornea includes a molding lens. The molding lens includes an external surface having a concave shape to correspond to the desired shape of the cornea. Heating and cooling elements are located with the…

  1. Method of refractive surgery

Wakil, Youssef Salih, Thornton, Spencer P., Pallikaris, Ioannis G., Eyesys-Premier, Inc.

A novel method and apparatus is presented for the performance of refractive surgery. The success of refractive surgery, particularly astigmatic refractive surgery, varies with the intuition and skill of the surgeon yielding a consistency of results…

  1. Device For Measuring Aberration Refraction of the Eye

MOLEBNY, Vasyl, PALLIKARIS, Ioannis, CHYZH, Igor, SOKURENKO, Vyacheslav, NAOUMIDIS, Leonidas, WAKIL, Joussef, TRACEY TECHNOLOGIES, L.L.C.

An instrument for measuring aberration refraction of an eye is provided, having a lens system defining an instrument optical axis, and an alignment device for aligning the visual axis of the eye with the instrument optical axis. A light source (1)…

  1. Locating the center of the entrance pupil of an eye after pupil dilation

Gray, Gary P., Gauthier, Charline A., Pallikaris, Ioannis G., Autonomous Technologies Corporation

A method and system are provided for locating the center of the entrance pupil of an eye after the pupil thereof has been dilated. A first image of an eye is formed prior to pupil dilation. The center of the undilated pupil is referenced to a…

  1. Method of refractive surgery

Wakil, Youssef Salih, Thornton, Spencer P., Pallikaris, Ioannis G., Eyesys Technologies, Inc.

A novel method and apparatus is presented for the performance of refractive surgery. The success of refractive surgery, particularly astigmatic refractive surgery, varies with the intuition and skill of the surgeon yielding a consistency of results…

  1. Procedure for removal of soft eye tissue

Pallikaris, Ioannis

A surgical procedure and device are used to precisely remove soft tissue from the eye. For example, a corneal epithelial layer is removed from the eye as part of a photorefractive keratectomy (PRK) or phototherapeutic keratectomy (PTK) procedure. In…

  1. Device for separating the epithelium layer from the surface of the cornea of an eye

Pallikaris Ioannis, Charilaos Ginis

The EpiLASIK procedure enables laser corrections to the eye without needing to make a cut through the eye. The removal of the need for a “stromal cut” (through the eye) is seen as a major advancement over the most commonly performed procedure known as LASIK.

Ioannis Pallikaris received his medical degree at the University of Thessaloniki, Greece (1972) and completed his residency and PhD thesis at the University of Zurich, Switzerland (1981). During these years, he also completed graduate studies at the University of Munich (Institute of Physiological Optic, 1978), at the University of Vienna (Ultrasound in Ophthalmology, 1979), and at the University of Zurich (Department of microvascular surgery, 1980).

Subsequently, he received an honorary consultant position at the Hippocration Hospital of Thessaloniki, Greece (1981-1986), and became Director of the Ophthalmology Clinic Hospital of Chania, Greece (1986-1988). He has been a Professor of Ophthalmology at the University of Crete since 1996. Over the course of the years at the University of Crete, he became the founder and director of the Vardinoyannion Eye Institute of Crete (VEIC, 1989) and Institute of Vision and Optics (IVO, 2005), chairman of the Department of Ophthalmology at the University of Crete, and the director of the Eye Clinic of the University Hospital of Heraklion, Greece (1996-2004). Ioannis Pallikaris was the rector of the University of Crete from 2004 to 2011, he was President of the European Society of Cataract and Refractive Surgery (ESCRS) from 2006 to 2008 and while he is also a Board member of ESCRS from 2011.

His research interests expand in all fields of ophthalmology, including refractive surgery, visual optics, medical lasers, biopolymers, retinal surgery and image analysis, and the design and development of microsurgical instrumentation. While today he has a broad field of interests, his most significant impact is in refractive surgery, in which he is considered internationally as one of the most opinionated leaders. At his early years, he published three breakthrough articles related to the development and investigation of laser in situ keratomileusis (LASIK). Since then, he had a great impact in the field of ophthalmology while today he is considered “the father of LASIK”, the most world wide acknowledged and used technique in refractive surgery today.

In many countries LASIK is the most frequent surgical operation on the human body (followed by cataract surgery). Prof. Pallikaris has published approximately 198 articles in international peer-reviewed scientific journals and 27 articles in national peer-reviewed scientific journals. He is the editor of 5 books in ophthalmology, the most notable one being the book LASIK, a reference point for refractive surgeons worldwide. Moreover, he is the author or co-author of 17 invited chapters in International scientific books, while he is a reviewer in 5 international peer-reviewed journals. He has more than 2264 citations, while he holds more than 20 patents. In addition, he has been an invited speaker in more than 250 international conferences from 1998-2017, has over 270 and 190 presentations in international and Greek conferences, respectively. Finally, he has been awarded 25 international awards, most notably the “Barraquer award” from the American Academy of Ophthalmology (1997) for his groundbreaking contribution to refractive surgery. Recently, he published a book on prebyopia (Presbyopia: Origins, Effects, and Treatment. Authors: Ioannis Pallikaris, W. Neil Charman, Sotiris Plainis – ISBN-10: 1617110264).

Translational research in the Institute of Vision and Optics (IVO)

Prof. I. Pallikaris has been essential in expanding the revolutionary field of refractive surgery and creating the appropriate grounds for the opening of new and exciting applications in this field. His initial contributions with the development of LASIK had a direct impact on the newly formed, developed and investigated techniques today. Concurrently, the development of this groundbreaking technique had an enormous effect not only on the surgical field but also on the technological aspects of the associated instrumentation. Nonetheless, he continued to educate himself and support alternative fields in ophthalmology related to vision as a whole and not just from the medical view of the field. Moreover, Prof. Pallikaris and his collaborators implement a number of clinical investigations in collaboration with various medical companies as part of mutual research protocols. Some of these research protocols were performed for the US Food and Drug Administration with very important outcomes for the safety, reliability and effectiveness of new systems used in Ophthalmology.

In terms of systems, devices and instruments used in ophthalmology, he is contributing to this field by designing and developing new specialized instruments and systems. The TRACEY device, developed in collaboration with the Kiev Institute of Biomedical Technology (Ukraine) was one of the first commercial instruments for the measurement of the optical aberrations of the human eye and the assessment of retinal image quality. Under his guidance a precision machining workshop was deployed in the Institute of Vision and Optics of the University of Crete. It is remarkable, that the most experienced (and well equipped) machining workshop in the whole University of Crete belongs to the department of Ophthalmology. This workshop, following a quality control system in compliance to ISO 9001 is performing R&D and small scale manufacturing work (also irrelevant to ophthalmology) for other departments and the local industry. Apart from the expansion and inclusion of researchers in a variety of fields such as physics, optics, and engineering, he has strongly supported and provided a spark for new and younger scientists to accomplish their goals within the field of ophthalmology. Many of the graduates and post graduates students have gone to highly successful areas nationally and internationally and have contributed significantly to the scientific community. As it was mentioned earlier, education constitutes one of the basic activities of IVO as it fulfills its academic mission. Mini Fellowships in refractive surgery addressed towards ophthalmologists, optometrists, and opticians, conference organizations such as the Aegean Cornea and Aegean Retina with the participation of distinguished scientists, the interdisciplinary postgraduate program with the contribution of IVO and the collaboration of the departments of Medicine, Physics, and Mathematics of the University of Crete with the objective of the formation of scientists with a high level of education capable to follow careers in hospitals, medical centers, private enterprises that develop and implement devices in the fields of visual science, as well as in Universities and Research Institutes as academic – research personnel, are examples of the educational activities that he has initiated.

His current clinical expertise is on “Refractive lasers , FemtoLasik , Smile , Advanced PRK , “keratoconous and high Asrigmatism with Cross linking , intracorneal rings , Cornea traspalation “ , “ High Myopia Astigmatism and Hyperopia with Intraocular Phacik IOL “ “ Presbyopia with Premium lenses , multifocals , intracorneal inlays “